Searching for Homologous Genes Using Daisychain.

Area of Science:

• Genomics
• Bioinformatics
• Comparative Genomics

Background:

• Genome assemblies are essential genomics tools, with falling sequencing costs enabling multiple references for many species.
• Comparing genome assemblies and their annotations presents challenges due to varying quality and gene identification.
• Visualizing homologous or related genes across different genome assemblies is crucial for comparative studies.

Purpose of the Study:

• To introduce a novel workflow for searching and visualizing related genes across multiple genome assemblies.
• To present Daisychain, a web-based tool designed to facilitate gene comparison between different genome assemblies.

Main Methods:

• Development of a workflow integrating gene search and visualization functionalities.
• Implementation of Daisychain as an accessible web-based platform for comparative genomics research.

Main Results:

• Daisychain enables researchers to effectively search for and visualize related genes across diverse genome assemblies.
• The tool addresses the need for comparing genes with different identifiers in various assembly contexts.

Conclusions:

• Daisychain provides a valuable solution for researchers engaged in comparative genomics.
• The workflow and tool simplify the complex task of cross-assembly gene comparison, enhancing research efficiency.