Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

28.5K
Overview
28.5K
Allergic Drug Reactions01:27

Allergic Drug Reactions

965
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
965
Hypersensitivities01:30

Hypersensitivities

1.0K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vaccination for Patients With Immunosuppression and Altered Immunity: A Workgroup Report from the AAAAI Adverse Reactions to Drugs, Biologics, and Vaccines Committee and the Autoimmunity and Altered Immune Response Committee.

The journal of allergy and clinical immunology. In practice·2026
Same author

Reply to "Touchstones of compassionate care in allergy-immunology beyond artificial intelligence: connection and generational legacy".

The journal of allergy and clinical immunology. In practice·2026
Same author

Big Data and Artificial Intelligence: Current State and Future Opportunities in Allergy and Immunology.

The journal of allergy and clinical immunology. In practice·2025
Same author

Improving Adherence in Allergy Care: Challenges and Solutions.

The journal of allergy and clinical immunology. In practice·2024
Same author

Racial and Ethnic Representation in Food Allergen Immunotherapy Trial Participants: A Systematic Review.

JAMA network open·2024
Same author

Pediatric penicillin allergy labels: Influence of race, insurance, and Area Deprivation Index.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2024
Same journal

Key factors in the diagnosis of sesame allergy in children.

Allergy and asthma proceedings·2026
Same journal

Immunoglobulin E-mediated pumpkin seed allergy in children: Case series and narrative review with a structured literature search.

Allergy and asthma proceedings·2026
Same journal

Predictors of delayed treatment-free remission with omalizumab in chronic spontaneous urticaria.

Allergy and asthma proceedings·2026
Same journal

The digital front door: A national analysis of U.S. allergy and immunology fellowship program web sites.

Allergy and asthma proceedings·2026
Same journal

The impact of dietary patterns on the risk of asthma in children.

Allergy and asthma proceedings·2026
Same journal

The alpha-gal syndrome: Understanding the role of tick bites, and the delays in severe anaphylaxis.

Allergy and asthma proceedings·2026
See all related articles

Related Experiment Video

Updated: Sep 5, 2025

Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.5K

Pediatric subcutaneous allergen immunotherapy.

Sonya Parashar, Aarti Pandya, Jay M Portnoy

    Allergy and Asthma Proceedings
    |July 12, 2022
    PubMed
    Summary
    This summary is machine-generated.

    Subcutaneous immunotherapy (SCIT) offers long-term benefits for allergic rhinitis and asthma in children, potentially preventing new allergies and asthma development. While risks exist, SCIT can be a safe and effective treatment option when carefully managed.

    More Related Videos

    Basophil Activation Test for Allergy Diagnosis
    07:22

    Basophil Activation Test for Allergy Diagnosis

    Published on: May 31, 2021

    8.5K
    Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
    16:56

    Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

    Published on: August 30, 2014

    17.1K

    Related Experiment Videos

    Last Updated: Sep 5, 2025

    Antigenic Liposomes for Generation of Disease-specific Antibodies
    10:31

    Antigenic Liposomes for Generation of Disease-specific Antibodies

    Published on: October 25, 2018

    12.5K
    Basophil Activation Test for Allergy Diagnosis
    07:22

    Basophil Activation Test for Allergy Diagnosis

    Published on: May 31, 2021

    8.5K
    Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
    16:56

    Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

    Published on: August 30, 2014

    17.1K

    Area of Science:

    • Allergy and Immunology
    • Pediatric Pulmonology

    Background:

    • Subcutaneous immunotherapy (SCIT) is a standard treatment for allergic rhinitis and asthma.
    • It serves as an adjunct to conventional medical management, offering potential long-term symptom resolution.
    • SCIT can prevent new aeroallergen sensitizations and reduce asthma development risk in children.

    Purpose of the Study:

    • To evaluate the benefits and risks of SCIT in pediatric patients.
    • To explore the advantages of accelerated SCIT schedules for children.
    • To address special considerations for administering SCIT to children.

    Main Methods:

    • Review of existing literature on SCIT in pediatric populations.
    • Analysis of standard versus accelerated SCIT dosing schedules.
    • Identification of pediatric-specific challenges and safety measures.

    Main Results:

    • SCIT provides significant benefits for children, including medication adherence and reduced asthma progression.
    • Accelerated schedules offer practical advantages for pediatric treatment coordination.
    • Key considerations include needle phobia, injection comfort, consent, and communication.

    Conclusions:

    • SCIT is a safe and beneficial therapeutic option for children with allergic rhinitis and asthma.
    • Careful consideration of pediatric-specific factors is crucial for successful SCIT implementation.
    • Optimized scheduling can enhance treatment feasibility for young patients and their families.