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Updated: Sep 5, 2025

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Sub-aortic membrane - A three-dimensional echocardiographic perspective
Aidan Sharkey1, Nikita Ovtchinnikov1, Feroze Mahmood1
1Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Introduction:
Subaortic membrane is an uncommon cause of left ventricular outflow tract obstruction.
Discussion:
Whereas traditionally described of as a membrane, it is in fact a discreet circumferential shelf of raised endocardium in the left ventricular outflow tract, causing a fixed outflow obstruction. The circumferential nature of subaortic membranes is poorly appreciated on 2-dimensional imaging.
Conclusion:
Using a three-dimensional imaging and recently available on-cart rendition techniques of acquired images, we were able to better visualize the true extent of a sub-aortic membrane while also gaining insight into its origin and structure.

