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How Should We Regulate Heritable Human Genome Editing in Australia?

Dianne Nicol1, Christopher Rudge2, Rebecca Paxton3

  • 1Adjunct Professor of Law, Centre for Law and Genetics, University of Tasmania.

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|July 12, 2022
PubMed
Summary

Heritable human genome editing, the modification of DNA passed to future generations, is currently banned in Australia. This paper explores historical context and community views to inform future regulations on this reproductive technology.

Keywords:
citizens' juryembryo researchgovernance of genome editingheritable human genome editingmitochondrial donation

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Area of Science:

  • Genetics
  • Bioethics
  • Reproductive Technology

Background:

  • Heritable human genome editing involves altering DNA that will be passed to offspring.
  • This technology is prohibited in many countries, including Australia.
  • Australia's current laws on reproductive technologies are influenced by technological progress and societal reactions.

Purpose of the Study:

  • To examine the historical context of Australia's laws on heritable human genome editing.
  • To analyze how community responses to genome editing advancements may influence future legal reforms.
  • To establish a framework for developing a responsive regulatory environment for heritable human genome editing in Australia.

Main Methods:

  • Historical analysis of legislative and technological developments.
  • Examination of societal attitudes and ethical considerations.
  • Review of current and potential future regulatory frameworks.

Main Results:

  • Australia's regulatory landscape for reproductive technologies has evolved due to technological innovation and public discourse.
  • Community perceptions significantly impact the trajectory of law reform in emerging scientific fields.
  • Existing prohibitions on heritable human genome editing reflect a cautious societal approach.

Conclusions:

  • Future regulations for heritable human genome editing in Australia must balance technological capabilities with ethical norms and social values.
  • Understanding the interplay between scientific advancement and public opinion is crucial for effective governance.
  • Proactive engagement with ethical considerations and societal values will shape a responsible regulatory future for human genome editing.