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Updated: Sep 5, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
A modified microscopic-endoscopic bilateral transseptal approach for pituitary adenoma
Chao Shen1,2,3,4,5, Bojie Yang6,7,8,9,10
1Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, No. 12, Middle Urumqi Road, Shanghai, China.
Background:
Endoscopic transnasal surgery for tumors in the sellar region has become popular across the globe. However, postoperative nasal outcomes related to endoscopic transnasal surgery have yet to be described in detail.
Method:
Here, we introduce a modified microscopic-endoscopic bilateral transseptal approach for the surgical treatment of tumors in the sellar region. This technique yielded satisfactory postoperative nasal outcomes without any loss of the visual advantages associated with endoscopy.
Conclusion:
The modified microscopic-endoscopic bilateral transseptal approach described herein is a minimally invasive endoscopic transnasal approach and results in satisfactory postoperative outcomes in terms of nasal structure and olfactory function.

