Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tonsillitis II: Management

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Pneumonia IV: Management

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

Tonsillitis I: Introduction

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Staff Perspectives of Single-use versus Reusable Sterile Textiles: A Qualitative Analysis.

The Journal of surgical research·2026

Same author

A review of artificial intelligence in healthcare supply chains: untapped potential?

BMC health services research·2026

Same author

Is targeted cytomegalovirus testing of infants feasible in Western Australia? An observational study.

BMJ public health·2026

Same author

High rates of suppurative otitis media among children attending urban clinics in Goroka, Eastern Highlands Province, Papua New Guinea: a cross-sectional study.

The Lancet regional health. Western Pacific·2026

Same author

Wideband Absorbance Among Aboriginal and/or Torres Strait Islander and Non-Aboriginal Children With Suspected Otitis Media Living in an Australian Urban Area.

Ear and hearing·2026

Same author

The effects of sunlight exposure on mortality: a systematic review of epidemiological studies.

NIHR open research·2025

Search research articles

Related Experiment Video

Updated: Sep 5, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Published on: March 16, 2018

Systemic antibiotics for chronic suppurative otitis media.

Lee-Yee Chong¹, Karen Head², Katie E Webster²

¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

The Cochrane Database of Systematic Reviews

|July 12, 2022

Summary

Systemic antibiotics show uncertain benefits for chronic suppurative otitis media (CSOM) ear discharge. Evidence is limited, with little to no difference when added to topical treatments, and adverse effects are poorly reported.

More Related Videos

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Related Experiment Videos

Last Updated: Sep 5, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Published on: March 16, 2018

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Area of Science:

Otolaryngology
Infectious Diseases
Pharmacology

Background:

Chronic suppurative otitis media (CSOM) is a persistent middle ear infection causing discharge and hearing loss.
Systemic antibiotics are a common treatment for CSOM, targeting causative microorganisms.

Purpose of the Study:

To evaluate the effectiveness of systemic antibiotics in treating chronic suppurative otitis media (CSOM).

Main Methods:

Systematic review and meta-analysis of 18 randomized controlled trials (RCTs) involving 2135 participants.
Included trials compared systemic antibiotics (oral or intravenous) against placebo/no treatment or other systemic antibiotics.
Outcomes assessed included resolution of ear discharge, health-related quality of life, ear pain, hearing, and complications.

Main Results:

Evidence is very uncertain regarding the efficacy of systemic antibiotics alone compared to placebo for ear discharge resolution.
When systemic antibiotics were added to topical treatments, there was little to no difference in discharge resolution (low-certainty evidence).
Limited data prevented conclusions on the comparative effectiveness of different antibiotic classes, and adverse events were poorly reported.

Conclusions:

The evidence for the efficacy of systemic antibiotics in CSOM is limited and of very low to low certainty.
Systemic antibiotics may offer little to no additional benefit when used with topical treatments for CSOM.
Poor reporting of adverse effects necessitates caution regarding the use of systemic antibiotics for CSOM.