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The Effects of Skin Temperature Changes on the Integrity of Skin Tissue: A Systematic Review
Tiziana Mifsud1, Chiara Modestini, Anabelle Mizzi
1At the University of Malta, Msida, Tiziana Mifsud, MSc, MPodA, and Chiara Mondestini, BSc, MPodA, are Research Support Officers, Mater Dei Hospital; Annabelle Mizzi, PhD, FFPM RCPS (Glasg), is Lecturer, Faculty of Health Science; Owen Falzon, PhD, is Senior Lecturer and Researcher, Centre for Biomedical Cybernetics; Kevin Cassar, MD, FRCS (Edin), MMed (Dund), MD (Aberd), FRCS, FFStEd, is Professor and Vascular Surgeon, Mater Dei Hospital; and Stephen Mizzi, PhD, FFPM RCPS (Glasg), is Lecturer and Researcher, Faculty of Health Science.
Objective:
To determine whether changes in skin temperature can affect the integrity of skin.
Methodology:
The authors conducted a systematic literature search as per the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. They searched the CINAHL (Cumulative Index to Nursing and Allied Health Literature), Cochrane, MEDLINE Complete, Academic Search Ultimate, and HyDi databases for articles examining the effects of skin temperature on skin integrity published through April 2020. Two independent reviewers scored the methodologic quality of the 13 included studies.
Results:
Only 11 studies were included in the qualitative analysis, as the other two articles had a critical risk of bias. There is strong evidence to indicate that an increase in skin temperature leads to changes in skin structure and function. However, ulcer formation was more affected by intrinsic and extrinsic factors, rather than by temperature alone.
Conclusion:
Further high-quality randomized controlled trials are required to investigate the direct effect of skin temperature on ulceration.
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