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Vitamin D assessment in patients with COVID-19 virus and correlation with severity
Tarek M Yosef1, Shereen A Saleh1, Sara Fekry Ali1
1Gastroenterology, Hepatology and Internal Medicine Department, Ain Shams University, Cairo, Egypt.
Background:
Vitamin D may play a vital role in preventing the multi-system consequences of COVID-19 infections. The aim of this study is to evaluate the potential association between mean serum levels of vitamin D and COVID-19 and its correlation with severity and mortality.
Results:
A case-control study conducted on 80 Egyptian patients admitted at Ain Shams University designated hospitals, Cairo, Egypt, from March 2021 to September 2021. Regarding the laboratory investigations, we found that COVID-19 cases have significantly lower lymphocytic counts than controls. Regarding vitamin D, this study showed a statistically significant positive correlation between vitamin D and lymphocytes, and there were statistically significant negative correlations between vitamin D, neutrophil-lymphocyte ratio, C-reactive protein, blood urea nitrogen, serum creatinine, aspartate aminotransferase, alanine aminotransferase, ferritin, lactate dehydrogenase, and D-dimer.
Conclusion:
This study confirms that vitamin D deficiency is associated with the severity of COVID-19 clinically and laboratory.
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