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Human monkeypox coinfection with acute HIV: an exuberant presentation
Diogo de Sousa1, João Patrocínio1, Joana Frade1
1Department of Dermatology, 218728Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal.
International Journal of STD & AIDS
|July 13, 2022
Summary
This case report details a 24-year-old male with concurrent monkeypox (MPX) and acute HIV infection. The patient presented with disseminated papules, including characteristic perianal lesions, highlighting MPX clinical diversity.
Area of Science:
- Dermatology
- Infectious Diseases
- Virology
Background:
- Human monkeypox (MPX) is a zoonotic viral disease endemic to Africa, recently observed in non-African countries.
- Co-infection with other sexually transmitted infections, including HIV, is a growing concern during MPX outbreaks.
Observation:
- A 24-year-old male presented with a disseminated rash consistent with MPX.
- The patient had a concurrent diagnosis of acute Human Immunodeficiency Virus (HIV) infection.
- Distinctive perianal lesions, described as grouped, umbilicated papules in a kissing configuration, were noted.
Findings:
- Laboratory tests confirmed acute HIV infection.
- Swab samples from skin lesions tested positive for the monkeypox virus.
- The clinical presentation expanded the known spectrum of MPX manifestations.
Implications:
- This case highlights the importance of considering MPX in patients with acute HIV infection presenting with dermatological symptoms.
- Healthcare providers should be aware of the diverse clinical presentations of MPX, including atypical lesion distribution.
- Early recognition and diagnosis of MPX co-infection are crucial for appropriate patient management and public health response.
