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Long-term outcomes of robot-assisted radical thymectomy for large thymomas: A propensity matched analysis
Stefano Bongiolatti1, Alberto Salvicchi1, Valerij Puzhlyiakov1
1Thoracic Surgery Unit, Careggi University Hospital, Florence, Italy.
Background:
The aim of this study was to evaluate the long-term results of robot-assisted (RATS) thymectomy in the treatment of large thymomas, defined as larger than 5 cm.
Methods:
We retrospectively reviewed 106 thymectomies from 2010 to 2020, creating two groups based on the surgical approach (open or RATS) and size. Kaplan-Meier and Cox-regression were used to estimate and identify risk factors of oncological outcomes. To perform a well-balanced analysis, a propensity score matched (PSM) analysis was conducted for large thymomas.
Results:
From 2015, we performed 54 RATS thymectomies: 53.7% (n = 29) for small and 46.3% (n = 25) for large thymomas. Conversions were similar and all patients had a complete resection. The overall (82% vs. 92%, p = 0.57) and disease-free survival were comparable between RATS and open (92.5% vs. 93%, p = 0.67), outcomes confirmed after PSM for large thymomas.
Conclusions:
RATS thymectomy could be considered a valid option in selected patients with large thymomas.
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