Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

3.0K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.0K
Hypertension I: Introduction01:28

Hypertension I: Introduction

69
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
69
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

67
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
67
Alterations in Blood Pressure01:30

Alterations in Blood Pressure

1.4K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
1.4K
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

46
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
46
Hormonal Regulation of Blood Pressure01:17

Hormonal Regulation of Blood Pressure

3.1K
Endocrinal or hormonal intervention in the cardiovascular system is predominantly exerted by the catecholamines - epinephrine and norepinephrine, as well as a slew of hormones that interact with renal function to modulate blood volume.
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beliefs and counseling practices among dermatologists regarding sexual and other adverse effects of finasteride.

International journal of impotence research·2023
Same author

Battling the Testosterone Clinics and Websites.

Journal of general internal medicine·2022
Same author

Detransition Among Transgender and Gender-Diverse People-An Increasing and Increasingly Complex Phenomenon.

The Journal of clinical endocrinology and metabolism·2022
Same author

The growing and interdisciplinary field of transgender health.

Andrology·2021
Same author

How routine pharmacovigilance failed to identify finasteride's persistent sexual side effects.

Andrology·2021
Same author

Weight gain and obesity rates in transgender and gender-diverse adults before and during hormone therapy.

International journal of obesity (2005)·2021

Related Experiment Video

Updated: Sep 4, 2025

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

913

Hypertension in transgender individuals.

Michael S Irwig1,2

  • 1Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. mirwig@bidmc.harvard.edu.

Journal of Human Hypertension
|July 13, 2022
PubMed
Summary

Hypertension significantly impacts transgender and gender-diverse individuals. Routine blood pressure monitoring is crucial, especially during gender-affirming hormone therapy, which can influence blood pressure levels.

More Related Videos

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

840
Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells
09:29

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Published on: March 5, 2019

5.8K

Related Experiment Videos

Last Updated: Sep 4, 2025

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

913
Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

840
Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells
09:29

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Published on: March 5, 2019

5.8K

Area of Science:

  • Cardiovascular Health
  • Endocrinology
  • Public Health

Background:

  • Transgender and gender-diverse (TGD) populations face increasing recognition, yet hypertension prevalence data remains scarce.
  • Existing research on hypertension in TGD individuals is limited, necessitating further investigation.

Purpose of the Study:

  • To summarize current data on hypertension prevalence in TGD populations.
  • To compare hypertension rates in TGD individuals with cisgender populations.
  • To investigate the impact of gender-affirming hormone therapy (GAHT) on blood pressure and hypertension.

Main Methods:

  • Systematic review of existing literature on hypertension prevalence in TGD populations.
  • Comparative analysis of hypertension rates between TGD and cisgender individuals.
  • Exploration of GAHT effects on blood pressure parameters.

Main Results:

  • Hypertension affects a significant proportion of TGD people.
  • Estrogen-based GAHT was linked to decreased systolic blood pressure.
  • Testosterone-based GAHT was linked to increased systolic blood pressure.

Conclusions:

  • Routine blood pressure monitoring is recommended for TGD individuals.
  • GAHT initiation requires careful cardiovascular monitoring due to potential blood pressure changes.