Related Experiment Video
Updated: Sep 4, 2025

12:39
DUCT: Double Resin Casting followed by Micro-Computed Tomography for 3D Liver Analysis
Published on: September 28, 2021
3.4K
Chronic Infection and Nodule Formation following Deoxycholate Injection
Shahab Shahid1, Fawaz Al-Hassani1
1St Andrew's Centre for Plastic Surgery and Burns, Broomfield Hospital, Chelmsford, United Kingdom.
Archives of Plastic Surgery
|July 14, 2022
Summary
Improper use of Aqualyx, an injectable fat-dissolving treatment, led to severe patient complications including skin necrosis and painful nodules. Proper training is crucial for safe administration of cosmetic injectables.
Area of Science:
- Aesthetics
- Dermatology
- Cosmetic Procedures
Background:
- Aqualyx is an European Union-approved injectable solution for localized fat reduction, composed of deoxycholate, saline, and buffering compounds.
- It is exclusively sold to healthcare professionals trained in intralipotherapy.
- Improper administration can lead to adverse events.
Purpose of the Study:
- To report a case of severe complications following the non-professional and superficial administration of Aqualyx.
- To highlight the importance of proper training and competence in cosmetic procedures.
Main Methods:
- A case report detailing patient presentation and clinical course.
- Diagnostic ultrasound to characterize the lesion.
- Clinical observation of treatment outcomes.
Main Results:
- The patient experienced severe pain, inability to sit, localized skin necrosis, and palpable collections post-injection.
- Ultrasound revealed a superficial hypoechoic lesion without deeper infection.
- Multiple painful nodules ruptured, causing purulent and bleeding lesions.
Conclusions:
- This case underscores the critical need for qualified healthcare professionals and appropriate technique when administering injectable fat-dissolving treatments like Aqualyx.
- Suboptimal administration can result in significant morbidity and necessitate further medical intervention.

