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Bilateral vs Unilateral Hypoglossal Nerve Stimulation in Patients With Obstructive Sleep Apnea
Clemens Heiser1, J Ulrich Sommer1, Benedikt Hofauer1
1Department of Otorhinolaryngology-Head and Neck Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
OTO Open
|July 14, 2022
Summary
Bilateral hypoglossal nerve stimulation (biHNS) shows comparable safety and effectiveness to unilateral hypoglossal nerve stimulation (uniHNS) for obstructive sleep apnea. Further long-term studies are needed to confirm biHNS stability.
Area of Science:
- Neurology
- Sleep Medicine
- Biomedical Engineering
Background:
- Obstructive sleep apnea (OSA) is a common sleep disorder.
- Unilateral hypoglossal nerve stimulation (uniHNS) is an established treatment for OSA.
- Bilateral hypoglossal nerve stimulation (biHNS) presents a novel therapeutic approach.
Purpose of the Study:
- To compare the clinical outcomes of the first 10 bilateral hypoglossal nerve stimulation (biHNS) cases with the first 10 unilateral hypoglossal nerve stimulation (uniHNS) cases.
- To evaluate the safety and efficacy of biHNS versus uniHNS in OSA patients.
Main Methods:
- Prospective data analysis of an international multicenter comparative clinical trial.
- Inclusion of the first 10 biHNS (Genio System) and 10 uniHNS (Inspire II) patients.
- Outcome assessment at 3 months post-surgery, including AHI, oxygen saturation, and Epworth Sleepiness Scale.
Main Results:
- Both biHNS and uniHNS groups showed significant reductions in Apnea-Hypopnea Index (AHI) and Epworth Sleepiness Scale scores after 3 months.
- No significant difference in AHI reduction was observed between the biHNS and uniHNS groups.
- Demographics and body mass index were comparable between the two groups.
Conclusions:
- Preliminary data suggest biHNS is a safe and effective alternative to uniHNS for OSA treatment.
- Long-term follow-up in a larger patient cohort is necessary to validate the stability and long-term efficacy of biHNS.
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