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Using Human Milk Fortifiers to Improve the Preoperative Nutritional Status of Infants With Non-restricted Ventricular
Yun-Feng Lin1,2,3,4, Wen-Hao Lin4,5,6, Shi-Hao Lin4,5,6
1Department of Neonatology, Fujian Branch of Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Fuzhou, China.
Human milk fortifier (HMF) improved nutritional status in infants with ventricular septal defect (VSD) without increasing complications. This study highlights HMF as a safe and effective method for preoperative nutritional enhancement in these infants.
Area of Science:
- Pediatric Cardiology
- Neonatal Nutrition
- Clinical Research
Background:
- Infants with ventricular septal defect (VSD) often require nutritional support.
- Optimizing preoperative nutritional status is crucial for surgical outcomes in VSD patients.
Purpose of the Study:
- To evaluate the efficacy of human milk fortifier (HMF) in enhancing preoperative nutritional status in infants with non-restricted VSD.
- To assess the safety of HMF supplementation regarding gastrointestinal complications.
Main Methods:
- A prospective randomized controlled study involving 58 infants with non-restricted VSD.
- Intervention group received HMFs, control group received exclusive breastfeeding.
- Nutritional status and complications were assessed after 1 month.
Main Results:
- The HMF group showed significantly higher weight, head circumference, height, albumin, and prealbumin levels compared to the control group (p < 0.05).
- The HMF group had a significantly lower STRONGkids score, indicating improved nutritional status (p < 0.05).
- No significant differences in pneumonia, liver insufficiency, feeding intolerance, or jaundice were observed between groups.
Conclusions:
- HMF supplementation effectively improves preoperative nutritional status in infants with non-restricted VSD.
- HMF is a safe intervention, not associated with an increased risk of gastrointestinal complications.
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