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Case Report: Anterior Scleritis Presenting as a Primary Ocular Manifestation in Multisystem Inflammatory Syndrome in
Daisuke Matsubara1, Daisuke Tamura1, Yuka Kasuya2
1Department of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Insights
Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory condition linked to COVID-19, can cause severe eye issues. This case highlights anterior scleritis as a primary MIS-C symptom, emphasizing the need for ophthalmological evaluation.
Area of Science:
- Pediatric rheumatology
- Infectious diseases
- Ophthalmology
Background:
- Multisystem inflammatory syndrome in children (MIS-C) is a serious hyperinflammatory condition associated with prior SARS-CoV-2 infection.
- While mild ocular symptoms like conjunctivitis are common in MIS-C, severe eye manifestations are infrequently reported.
- Understanding the full spectrum of MIS-C symptoms, including ocular complications, is crucial for timely diagnosis and management.
Abstract:
Multisystem inflammatory syndrome in children (MIS-C) is a newly defined hyperinflammatory disease linked to antecedent coronavirus disease 2019. Patients with MIS-C present with various symptoms, and ocular findings such as mild bilateral conjunctivitis are relatively common. However, detailed descriptions of severe ocular reports associated with MIS-C are scarce in the current literature. Here we report a case of MIS-C in a Japanese boy, with severe eye manifestations in the form of anterior scleritis as the primary MIS-C symptom. Detailed ocular examinations by ophthalmologists may be key for clarifying the pathophysiology of MIS-C.
