Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Sep 4, 2025

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
12:03

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

12.5K

Primary Calvarial Ewing Sarcoma: A Case Series.

Sandeep Mohindra1, Manjul Tripathi1, Aman Batish1

  • 1Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Journal of Neurological Surgery. Part B, Skull Base
|July 14, 2022
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cervical Spine Movements With Single-Handed Versus Bimanual Cricoid Pressure Under Simulated Cervical Immobilization: A Randomized Controlled Trial.

Journal of neurosurgical anesthesiology·2026
Same author

Cytokine levels in serum and cerebrospinal fluid of patients with idiopathic intracranial hypertension.

Brain research·2026
Same author

Brain white matter microstructural integrity differences between pre-post buprenorphine-naloxone treated individuals with opioid use disorder: Evidence from a DTI study.

Psychiatry research. Neuroimaging·2026
Same author

Bilateral Opercular Syndrome in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Encephalomyelitis: An Unusual Presentation.

Annals of Indian Academy of Neurology·2026
Same author

Skin-Colored Nodular Facial Swelling in a Middle-Aged Female.

Indian dermatology online journal·2026
Same author

Ulcerated Plaque with Multifocal Necrotizing Lymphadenopathy in a Young Male.

Indian dermatology online journal·2026
Same journal

Geographic Trends and Disparities in Meningioma Mortality: A National Observational Study from 1999 to 2020 Utilizing the CDC Wonder Database.

Journal of neurological surgery. Part B, Skull base·2026
Same journal

Bioengineered Materials for Skull Base Reconstruction-Current Clinical Applications: Systematic Review and Meta-analysis.

Journal of neurological surgery. Part B, Skull base·2026
Same journal

Anatomical Variability of the Transverse and Sigmoid Sinus Grooves: Implications for Skull Base Surgery.

Journal of neurological surgery. Part B, Skull base·2026
Same journal

Microsurgical Treatment of Spheno-Orbital Meningiomas: The Clinical Significance of the Tumor Invasion into the Greater Sphenoid Wing.

Journal of neurological surgery. Part B, Skull base·2026
Same journal

Morphological Variability of Dural Venous Sinus Grooves and Internal Bony Findings: Clinical and Surgical Considerations.

Journal of neurological surgery. Part B, Skull base·2026
Same journal

Courthouses and Craniotomies: Medical Malpractice Indemnity Payments and Litigation Verdicts in Skull Base and Open Cerebrovascular Neurosurgical Practice in the United States throughout the 21st Century.

Journal of neurological surgery. Part B, Skull base·2026
See all related articles

Primary calvarial Ewing sarcoma (EWS) is a rare bone tumor affecting children and young adults. Surgical excision combined with adjuvant therapy offers a potential for favorable long-term outcomes in managing this condition.

Area of Science:

  • Oncology
  • Pediatric Oncology
  • Neurosurgery

Background:

  • Calvarial Ewing sarcoma (EWS) is an uncommon diagnosis within the spectrum of bony neoplasms.
  • This study focuses on the clinical presentation and management of primary calvarial EWS.

Purpose of the Study:

  • To present the experience in managing primary calvarial Ewing sarcoma.
  • To highlight the clinical and radiological characteristics of these rare tumors.
  • To update the literature on management strategies and outcomes.

Main Methods:

  • A retrospective analysis of a 12-year institutional database of pathologically confirmed EWS.
  • Inclusion of a literature search for comparative data on management and outcomes.
  • Evaluation of clinical data, radiological findings, surgical procedures, and treatment outcomes.
Keywords:
Ewingcalvariaprimaryradiology

More Related Videos

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

813
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.7K

Related Experiment Videos

Last Updated: Sep 4, 2025

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
12:03

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

12.5K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

813
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.7K

Main Results:

  • Eight patients (5 males, 3 females; age 6 months–19 years) with primary calvarial EWS were managed between January 2008 and December 2020.
  • All patients underwent wide local excision, with some requiring intradural resection or scalp reconstruction.
  • Adjuvant chemotherapy and radiotherapy were administered to all patients; 5-year follow-up showed 3 asymptomatic patients and 2 deaths.

Conclusions:

  • Primary calvarial EWS is a rare tumor predominantly affecting individuals in their first two decades of life.
  • Tumors can present as intracranial masses causing increased intracranial pressure or as subgaleal masses with cosmetic deformities.
  • Radical surgical excision followed by adjuvant therapy is associated with potentially favorable long-term outcomes.