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Updated: Sep 4, 2025
A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
Epidemiology, clinical, and laboratory profile of patients with hepatitis C: A prospective, observational study from
Bhupen Barman1, Akash Roy2, Arvind Nune3
1Associate Professor, Department of General Medicine, 56918North Eastern Indira Gandhi Regional Institute of health and Medical sciences, Shillong, India.
Abstract:
Low and middle-income countries (LMICs) contribute to 80% of the global hepatitis C virus (HCV) infection burden. Intravenous drug use (IVDU) is not uncommon in Northeastern India, thus contributing to HCV. Its epidemiology, clinical, and laboratory profile were studied in a tertiary care centre in northeastern India.HCV patients (age >18) of either sex were prospectively assessed for demographic, virological, and genotype distributions. Most were male (M: F, 5.8:1) with a mean age of 37.1 ± 11.8 years. The most common risk factor was IVDU(77.69%), followed by concomitant alcohol use in 69.2%. Besides genotype 3 (59.2%), genotype 1 (26.1%) and genotype 6 were also common (14.6%). The demographics, liver disease severity, and biochemical parameters were similar across genotypes.
