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Updated: Sep 4, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Photocatalyst-free Light-driven Dehydrogenation of Alcohols into Carbonyl Compounds under Mild Conditions
Qiangwen Fan1,2, Honglei Zhang2, Huijun Ren2
1Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, 330013, P. R. China.
Abstract:
Herein, we reported a photocatalyst-free, facile and eco-friendly method for conducting dehydrogenation of alcohols to corresponding aldehydes or ketones with high selectivity under mild conditions. The methodology exhibited outstanding tolerance with electron-donating and electron-withdrawing groups and afforded series of aldehydes or ketones in considerable yields. Furthermore, the plausible mechanism was investigated by control experiments and DFT calculations. The advantages of readily accessible, atomic economy and green reaction conditions for the present method will endow it with prospective application in chemical synthesis.
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