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Encephalic meningioangiomatosis in a cat
Megan P Corbett1, Brianna L Kopec2, Marc Kent2
1Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Summary
Meningioangiomatosis (MA), a rare vascular condition, is described in a cat with neurological signs. The study details its brain lesions, associated hemorrhage, and other organ involvement.
Area of Science:
- Veterinary Pathology
- Neuropathology
- Comparative Oncology
Background:
- Meningioangiomatosis (MA) is a rare meningovascular proliferative entity.
- MA has been primarily documented in humans and dogs.
- This report details a novel case of MA in a domestic shorthaired cat.
Purpose of the Study:
- To describe the clinical, imaging, gross, and histopathological findings of meningioangiomatosis in a feline patient.
- To characterize the unique features of feline MA, including extensive hemorrhage.
Main Methods:
- A 13-year-old domestic shorthaired cat presenting with acute neurological signs was studied.
- Magnetic Resonance Imaging (MRI) was performed to evaluate the brain lesions.
- Necropsy and histopathological examination, including immunohistochemistry (vimentin), were conducted.
Main Results:
- The cat exhibited acute behavioral changes, seizures, and neurological deficits.
- MRI revealed predominantly extraparenchymal hemorrhage.
- Histopathology confirmed meningioangiomatosis with spindle cells, extensive hemorrhage, mineralization, and associated suppurative pancreatitis and myonecrosis.
Conclusions:
- This case expands the known species affected by meningioangiomatosis.
- The significant hemorrhage associated with MA in this feline case is a notable finding.
- MA should be considered in the differential diagnosis of feline intracranial lesions with hemorrhagic components.
