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SARS-CoV-2 Variants in Rhode Island; May 2022 Update
Manjot Singh1, Vladimir Novitsky1, Kristin Carpenter-Azevedo2
1Warren Alpert Medical School, Brown University, Providence, RI.
Rhode Island Medical Journal (2013)
|July 14, 2022
Summary
Genomic surveillance tracked SARS-CoV-2 evolution in Rhode Island, identifying over 17,000 sequences. This data revealed shifts from variants being monitored (VBM) to the Omicron variant, aiding public health efforts.
Area of Science:
- Virology
- Genomics
- Epidemiology
Background:
- Genomic surveillance is crucial for identifying and tracking SARS-CoV-2 variants.
- This study provides an updated analysis of SARS-CoV-2 evolution within Rhode Island.
Purpose of the Study:
- To analyze the evolution of SARS-CoV-2 strains in Rhode Island.
- To identify circulating variants of concern (VOC), variants being monitored (VBM), and other non-VOC/non-VBM strains.
Main Methods:
- Retrieved publicly available SARS-CoV-2 sequences from Rhode Island via GISAID.
- Conducted genomic analyses to identify and track variant evolution.
Main Results:
- Analyzed 17,340 SARS-CoV-2 sequences from February 2020 to May 2022.
- Observed a transition from VBM (predominantly Delta) to the Omicron variant (VOC) starting December 2021.
- Identified 71 Delta and 44 Omicron sub-lineages, noting mutation occurrences across variants.
Conclusions:
- Statewide genomic surveillance effectively characterizes circulating SARS-CoV-2 variants.
- Monitoring viral evolution informs public health officials for effective COVID-19 mitigation strategies.
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