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Updated: Sep 4, 2025

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
Gut microbiota gestalt
Jonathan Melamed1, Gabrielle LeBlanc1, Michael G Constantinides1
1Department of Immunology & Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Abstract:
The pathogenicity of disease-associated microbes varies widely between individuals. In this issue of Cell Host & Microbe, Rice et al. demonstrate that interactions between intestinal commensals reciprocally modulate the host immune response to each microbe, ameliorating the inflammation caused by one and dampening antibody responses to the other.
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