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Hypertension as an Independent Risk Factor for In-Patient Mortality in Hospitalized COVID-19 Patients: A Multicenter
Hasan Mirza1, Muhammad Atif Masood Noori2, Hafsa Akbar3
1Internal Medicine, Berkshire Medical Center, Pittsfield, USA.
Cureus
|July 15, 2022
Summary
Hypertension is common in COVID-19 patients, but this study found it is not an independent risk factor for in-hospital mortality. After adjusting for other health conditions, hypertension did not significantly increase COVID-19 death risk.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Hypertension is a common comorbidity in COVID-19 patients and a risk factor for severe disease.
- Existing literature on hypertension's association with COVID-19 mortality is inconsistent.
- The independent impact of hypertension on COVID-19 mortality requires further investigation.
Purpose of the Study:
- To investigate hypertension as an independent risk factor for in-hospital mortality in COVID-19 patients.
- To analyze the association between hypertension and COVID-19 mortality after adjusting for confounding variables.
Main Methods:
- A multicenter retrospective analysis of 515 hospitalized COVID-19 patients from March to May 2020.
- Patients were categorized into hypertensive and normotensive groups.
- Demographic data, laboratory results, and in-hospital mortality were collected and analyzed.
Main Results:
- Overall in-hospital mortality was 25.3%.
- Hypertensive patients had a higher mortality rate but were also older and had more comorbidities.
- Multivariable logistic regression revealed no significant association between hypertension and COVID-19 mortality after adjusting for confounders.
Conclusions:
- Hypertension is not an independent risk factor for in-hospital mortality in COVID-19 patients.
- Comorbidities commonly found in hypertensive patients significantly influence COVID-19 outcomes.
- Further research should focus on managing multiple comorbidities in hypertensive COVID-19 patients.
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