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Published on: September 22, 2023
Four Acid-Base Disturbances in a Critically-Ill Patient Undergoing Emergent Abdominal Surgery
Orestes Mavrothalassitis1, Balkarn S Thind1, Ashish Agrawal1
1Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA, USA.
Perioperative acid-base imbalances in critically-ill surgical patients can stem from various causes beyond tissue hypoperfusion. Early recognition of conditions like starvation ketosis is crucial for accurate patient assessment and predicting outcomes.
Area of Science:
- Critical Care Medicine
- Surgical Pathology
- Acid-Base Physiology
Background:
- Lactic acidosis is a frequent complication in critically-ill surgical patients, often linked to tissue hypoperfusion.
- However, other acid-base disturbances can occur perioperatively and may be overlooked during acute resuscitation efforts.
- Focusing solely on surgical pathology can lead to missed diagnoses of concurrent medical conditions.
Observation:
- A 60-year-old woman with no prior medical history underwent exploratory laparotomy for a perforated umbilical hernia.
- Her perioperative management was complicated by multiple acid-base disturbances.
- Notably, starvation ketosis was identified as one of the concurrent metabolic abnormalities.
Findings:
- The case demonstrates that perioperative acid-base imbalances are multifactorial.
- Multiple concurrent acid-base disturbances, including starvation ketosis, can affect surgical patients.
- These imbalances require careful diagnosis beyond the immediate surgical issue.
Implications:
- Early and comprehensive recognition of acid-base disturbances is vital in surgical critical care.
- Accurate identification of all acid-base abnormalities aids in understanding concurrent medical pathology.
- This diagnostic approach improves the prediction of a patient's post-operative course and management strategy.
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