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Updated: Sep 4, 2025

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
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Biobank and Pathology Facility: A Successful Combination.

Adriana Alves1, Amanda Gibbon2, Sara Carvalho1

  • 1Pathology Translational Technology Platform, Cancer Institute, University College London London UK UCL/UCLH Biobank for Studying Health and Disease, Cancer Institute, University College London London WC1E 6DE UK.

Journal of Biomolecular Techniques : JBT
|July 15, 2022
PubMed
Summary

Integrating biobanks with pathology facilities improves financial sustainability and operational efficiency. This management strategy helps overcome funding challenges and reduces costs for biorepositories and associated services.

Keywords:
Biobankfinancial sustainabilityhistology

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Area of Science:

  • Biobanking and Biorepository Management
  • Health Services Research
  • Pathology and Laboratory Medicine

Background:

  • Financial sustainability is a major global challenge for biobanks due to limited funding and high operational costs.
  • Biobanks often struggle to balance their budgets, impacting their ability to provide essential services.
  • Effective governance and operational efficiency are crucial for biobank viability.

Purpose of the Study:

  • To explore the operational and financial interactions between a pathology facility and a biobank over three years.
  • To assess the impact of integrating biobank services with a pathology facility.
  • To identify strategies for improving biobank financial sustainability and operational efficiency.

Main Methods:

  • A 3-year (2017-2019) analysis of operational and financial data from the University College London (UCL)/UCL Hospitals Biobank for Studying Health and Disease and the associated Pathology Facility.
  • Examination of service request data, focusing on the types of services utilized (histology, sample collection, molecular biology).
  • Evaluation of the integrated management structure under the UCL Cancer Institute.

Main Results:

  • Most service requests primarily involved histology services, with a minority utilizing biobank archive or molecular biology services.
  • The study confirmed the inherent difficulty for biobanks to achieve financial sustainability independently.
  • Integration of the Pathology Facility and the Biobank under a unified management system demonstrated improved efficiency and cost reduction.

Conclusions:

  • Integrating biobanks with pathology facilities within a single laboratory management infrastructure is an effective strategy for enhancing operational efficiency.
  • This integrated approach offers a viable solution to overcome financial and operational challenges faced by biobanks.
  • The findings suggest that shared management and infrastructure can lead to significant cost savings and improved service delivery for both entities.