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Updated: Sep 4, 2025

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research
Published on: June 8, 2017
Middle ear effusion and newborn hearing screening
Hanin Karawani1, Wisam Matanis2, Shorook Na'ara2
1Department of Communication Sciences and Disorders, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel. hkarawani@staff.haifa.ac.il.
Congenital middle ear effusion (MEE) often causes newborn hearing screening failures. This condition is persistent, with a low spontaneous resolution rate, necessitating further follow-up for conductive hearing loss.
Area of Science:
- Pediatric Audiology
- Otolaryngology
- Neonatal Screening
Background:
- Middle ear effusion (MEE) is a common cause of failed newborn hearing screening.
- MEE can lead to conductive hearing loss, requiring extended follow-up.
- Understanding the long-term outcome of congenital MEE is crucial for effective management.
Purpose of the Study:
- To investigate the resolution rate and long-term fate of middle ear effusion in newborns who failed initial hearing screening.
- To assess the persistence of conductive hearing loss attributed to congenital MEE at a 1-year follow-up.
Main Methods:
- Retrospective analysis of medical records for newborns born between 2012-2013.
- Data extraction included Universal Newborn Hearing Screening (UNHS) results and follow-up audiological evaluations.
- Focus on infants diagnosed with conductive hearing loss due to MEE.
Main Results:
- 1.5% of 9527 newborns failed UNHS; 46 were diagnosed with MEE-related conductive hearing loss.
- Spontaneous MEE clearance occurred in 26% of cases.
- 57% had persistent effusion requiring further management, including ventilation tubes (22%) or continued monitoring (35%). 17% were lost to follow-up.
Conclusions:
- Congenital middle ear effusion causing UNHS failure and conductive hearing loss demonstrates significant persistence.
- Resolution rates for congenital MEE are lower compared to non-congenital MEE.
- Prolonged follow-up is essential for infants with congenital MEE.
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