Isolation and characterization of new iturins: iturin D and iturin E

Two new antibiotics, iturin D and iturin E, were isolated from a strain of Bacillus subtilis producing iturin A. These compounds belong to the iturin group, the acid hydrolysates contained alpha-amino acids Asp3, Glu1, Pro1, Ser1, Tyr1, and a mixture of n-C14, iso-C15, anteiso-C15, iso-C16 and n-C16 beta-amino acids. They differ from iturin A by the presence of a free carboxyl group in iturin D and a carboxymethyl group in iturin E.