Lower gastrointestinal function after surgery for deep endometriosis: A prospective cohort study

Area of Science:

• Gynecology
• Gastroenterology
• Surgical Oncology

Background:

• Deep endometriosis (DE) can significantly impact lower gastrointestinal function.
• Surgical intervention is a primary treatment modality for DE.

Purpose of the Study:

• To prospectively evaluate the long-term effects of laparoscopic surgery on lower gastrointestinal function in patients with DE.
• To assess changes in bowel pattern, bowel control, and quality of life post-surgery.

Main Methods:

• Prospective observational study of 149 patients with confirmed DE undergoing laparoscopic surgery.
• Utilized the International Consultation on Incontinence Questionnaire Anal Incontinence Symptoms and Quality of Life Module (ICIQ-B) for data collection.
• Assessed bowel function and quality of life at baseline, 6 weeks, 6 months, and 12 months post-surgery.

Main Results:

• Significant improvements observed in bowel pattern and quality of life scores following surgery.
• Bowel pattern scores improved consistently from pre-operation to 12 months post-surgery.
• Patients with direct lower gastrointestinal endometriosis involvement showed greater functional improvements.

Conclusions:

• Laparoscopic surgery offers significant long-term benefits for lower gastrointestinal function in patients with DE.
• Further research is warranted to identify patient subgroups who will most benefit from surgical intervention for bowel dysfunction.