Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor
Lingyuan Min1, Yongtian Yin2, Qingyang Zhao2
1Research Center of Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Ji'nan 250013, Shandong, China.
Abstract:
This study describes the characterization of one induced pluripotent stem cell line (iPSC) from a healthy female. It is crucial to use iPSCs derived from healthy individuals as controls in genetic disease studies. Thus, we established a human iPSC cell line derived from healthy people. The iPSC cell line was generated in our lab from the peripheral blood mononuclear cells (PBMCs) of a 28-year-old girl. The generated hiPSC line is free of episomal vectors, has a normal karyotype, expresses pluripotency markers and can differentiate into three germ layers in vivo.
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