Related Experiment Video
Updated: Sep 4, 2025

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
Author's response to the commentary: Neuromyelitis optica complicating COVID vaccinations and additional case reports
Nanthaya Tisavipat1, Chumpol Anamnart2, Weerapat Owattanapanich3
1Siriraj Neuroimmunology Center, Faculty of Medicine Siriraj Hospital Mahidol University, Bangkok 10700, Thailand.
Abstract:
Our article Newly diagnosed neuromyelitis optica spectrum disorders following vaccination: Case report and systematic review had instigated a critique that there were more cases of post-COVID-19-vaccination NMOSD. Indeed, after the systematic review was performed in July 2021, many reports have been published, and we have seen two new patients at our center as well. However, Finsterer's question on the subclinical activity of NMOSD prior to vaccination, although an interesting notion, was debatable. NMOSD is a relapsing disease with severe attacks. Investigations in our patients did not reveal robust evidence of prior subclinical attacks so far.

