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Published on: July 30, 2020
Tetrodotoxins in the flatworm Planocera multitentaculata
Rei Suo1, Makoto Tanaka1, Hikaru Oyama1
1Department of Marine Science and Resources, Nihon University, Fujisawa, Kanagawa, 252-0880, Japan.
Abstract:
The marine polyclad flatworm Planocera multitentaculata is known to possess high levels of tetrodotoxin (TTX), but the presence of TTX analogues in the species has been unexplored. In this study, TTX and several analogues such as 5,6,11-trideoxyTTX, monodeoxyTTXs, dideoxyTTXs, and 11-norTTX-6(S)-ol were identified in three adults and egg plates of P. multitentaculata using high resolution liquid chromatography-mass spectrometry (HR-LC/MS) for the first time.
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