Factors associated with the eruption of the impacted maxillary third molars after second molar extraction

In orthodontic treatment, the space left after extracting the maxillary second molar (MxM2) may be filled by the eruption of the impacted third molar (MxM3). However, little is known about the factors associated with the eruption of the impacted MxM3. We aimed to characterize the clinical factors associated with the time taken for MxM3 eruption after MxM2 extraction.

We analyzed factors associated with late MxM3 eruption (>500 days after MxM2 extraction) in 84 molars. Prespecified risk factors were entered into logistic regression models to estimate odds ratios (ORs).

The median duration between MxM2 extraction and MxM3 eruption was 302 days (interquartile range, 140-424). Significant factors associated with late MxM3 eruption included the proximity of the MxM3 root to the maxillary sinus floor (OR, 51.72), the distance between the occlusal plane of the MxM3 and the apical third of the MxM2 roots (OR, 16.56), MxM3 angulation and depth of ≥20° (OR, 5.58), ANB angle of <2° (OR, 9.05), and ≥1.5 mm distal movement of the maxillary first molar (MxM1) from its original position at the time of MxM2 extraction and MxM3 eruption (OR, 12.9). The probability of late MxM3 eruption was 0% (0 out of 30) with no risk, 6.9% (2 out of 29) with 1 risk factor, and 52% (13 out of 25) with ≥2 risk factors.

We identified 5 clinical factors associated with late MxM3 eruption after MxM2 extraction. The probability of late MxM3 eruption increased as the number of present risk factors increased. These findings can be used for risk stratification during orthodontic treatment.