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Risk Factors for Benign Convulsions With Mild Gastroenteritis
Cuiyun Fang1, Wei Fan2, Chunsheng Zhang2
1Department of Nursing, Liyang People's Hospital, Liyang, China.
Insights
Rotavirus infection and altered uric acid levels are key risk factors for benign convulsions with mild gastroenteritis (CwG). Decreased serum sodium and increased uric acid can signal early CwG onset in children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- Benign convulsions with mild gastroenteritis (CwG) are common in children.
- Identifying risk factors is crucial for early diagnosis and intervention.
Purpose of the Study:
- To investigate the risk factors for CwG.
- To provide a basis for early identification and diagnosis of CwG.
Main Methods:
- Retrospective analysis of 175 children (82 with CwG, 93 with acute gastroenteritis).
- Data included general information, clinical characteristics, and laboratory results.
- Multifactorial logistic regression was used to identify independent risk factors.
Main Results:
- Rotavirus infection (OR, 3.042), decreased serum sodium (OR, 0.811), and increased uric acid (OR, 1.018) were identified as independent risk factors for CwG.
- No significant differences were observed in gender, age, vomiting, or diarrhea between groups.
- Significant differences were noted in onset season, rotavirus, white blood cells, liver enzymes, serum sodium, and uric acid.
Conclusions:
- Gastroenteritis symptoms like vomiting and diarrhea do not predict CwG onset.
- Rotavirus is a significant risk factor for CwG.
- Decreased serum sodium and increased uric acid levels serve as early warning indicators for CwG.
Objective:
To investigate the risk factors for benign convulsions with mild gastroenteritis (CwG) and provide a basis for the early identification and diagnosis.
Method:
We selected children with CwG and acute gastroenteritis in the same period who attended the pediatric department of the Liyang People's Hospital from June 2018 to June 2021. A retrospective analysis of the general data, clinical characteristics, and laboratory test results of the two groups was performed. Finally, we conducted a multifactorial logistic regression analysis to derive the risk factors for CwG.
Results:
A total of 82 children were included in the CwG and 93 children were included in the acute gastroenteritis group. Univariate analysis showed no significant differences in gender, age, vomiting, diarrhea, neutrophil, lymphocyte, hemoglobin, platelets, and serum calcium. Statistically significant differences were found in onset season, rotavirus, white blood cells, aspartate aminotransferase, alanine transaminase, serum sodium, and uric acid. Finally, multifactorial logistic regression analysis showed rotavirus (OR, 3.042, 95% CI, 1.116-8.289, p = 0.030), serum sodium (OR, 0.811, 95% CI, 0.684-0.962, p = 0.016) and uric acid (OR, 1.018, 95% CI, 1.012-1.024, p = 0.000) to be independent risk factors.
Conclusion:
Characteristics of gastroenteritis symptoms such as vomiting and diarrhea cannot be used to predict the onset of CwG. Rotavirus is an independent risk factor for CwG, and decreased serum sodium and increased uric acid can be used as early warning indicators for CwG.
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