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Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
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Pioneering insights of extrachromosomal DNA (ecDNA) generation, action and its implications for cancer therapy

Zesheng Li1, Bo Wang1, Hao Liang1

  • 1Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin Medical University General Hospital, Tianjin, 300052, P.R. China.

International Journal of Biological Sciences
|July 18, 2022
PubMed

Keywords:
cancerextrachromosomal DNA (ecDNA)function of ecDNAintratumoural heterogeneityoncogene amplificationtumour evolution

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