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Left Atrial Cardiomyopathy - A Challenging Diagnosis

Fabienne Kreimer1, Michael Gotzmann1

  • 1University Hospital St. Josef-Hospital Bochum, Cardiology and Rhythmology, Ruhr University Bochum, Bochum, Germany.

Frontiers in Cardiovascular Medicine
|July 18, 2022
PubMed

Insights

Diagnosing left atrial cardiomyopathy (LACM) is crucial for preventing atrial fibrillation and strokes. This review proposes a diagnostic algorithm by combining various parameters to address LACM

Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • Left atrial cardiomyopathy (LACM) is linked to atrial fibrillation and embolic strokes.
  • Accurate diagnosis of LACM is clinically significant but challenging due to its heterogeneity.
  • Current diagnostic methods lack standardization, hindering precise classification and treatment.

Purpose of the Study:

  • To review current evidence on diagnosing LACM.
  • To discuss various diagnostic parameters for LACM.
  • To propose a standardized diagnostic algorithm for LACM.

Main Methods:

  • Comprehensive literature review of diagnostic techniques for LACM.
  • Analysis of electrocardiography, echocardiography, cardiac MRI, CT, electroanatomic mapping, genetic testing, and biomarkers.
  • Synthesis of data to propose a diagnostic algorithm.

Main Results:

  • Multiple techniques can identify atrial dysfunction, but reliable LACM diagnosis remains difficult.
  • Combining various parameters is beneficial for diagnosing LACM.
  • A proposed diagnostic algorithm aims to standardize LACM assessment.

Conclusions:

  • Standardized diagnostic criteria for LACM are needed for improved patient management and research.
  • The proposed algorithm integrates multiple parameters for more precise LACM diagnosis.
  • Further validation of the diagnostic algorithm is essential.

Keywords:
atrial cardiomyopathyatrial fibrillationdiagnosisdiagnostic algorithmembolic stroke of undetermined source

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