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Updated: Sep 4, 2025

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
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Association between Perceived Salt Intake and Arterial Stiffness.

Mengdi Jin1, Congliang Miao1, Lina An2

  • 1Department of Emergency and Critical Care, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.

Biomed Research International
|July 18, 2022
PubMed
Summary

High salt intake (SI) is linked to arterial stiffness in northern China. Consuming over 10g daily significantly increases the risk of developing this cardiovascular condition.

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Area of Science:

  • Cardiovascular Health
  • Public Health Research
  • Dietary Impact on Vascular Function

Background:

  • Arterial stiffness is a key indicator of cardiovascular health.
  • High salt intake is a prevalent dietary factor with potential vascular implications.
  • Understanding the relationship between salt consumption and arterial stiffness is crucial for public health initiatives.

Purpose of the Study:

  • To investigate the association between perceived salt intake levels and arterial stiffness.
  • To identify if high salt consumption is a risk factor for arterial stiffness in a community population.
  • To analyze the impact of daily salt intake on brachial-ankle pulse wave velocity (baPWV).

Main Methods:

  • A cross-sectional study involving 36,324 participants in northern China.
  • Participants were categorized into low (<6g), medium (6-10g), and high (>10g) daily salt intake groups.
  • Multivariate logistic regression analysis was used to assess the influence of salt intake on arterial stiffness (baPWV).

Main Results:

  • The average brachial-ankle pulse wave velocity (baPWV) was 1527.73 ± 355.61 cm/s.
  • High salt intake (>10g/day) was identified as an independent risk factor for arterial stiffness (baPWV ≥1400 cm/s).
  • The odds ratio for arterial stiffness in the high salt intake group was 1.17 (95% CI: 1.04-1.31) after adjusting for confounders.

Conclusions:

  • High salt intake is independently associated with increased arterial stiffness.
  • Reducing daily salt consumption may be a vital strategy for preventing arterial stiffness and cardiovascular disease.
  • Community-based interventions targeting salt intake are warranted in northern China.