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Maxillary Fungal Osteomyelitis Mimicking and Treated as Endodontic Pathosis
Sarang Suresh Hotchandani1, Feroze Ali Kalhoro1, Priya Rani Harjani1
1Department of Operative Dentistry, Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan.
Abstract:
Fungal osteomyelitis is a lethal opportunistic infection that affects only a small percentage of patients present to endodontists. It is a highly contagious infection that requires urgent treatment. We discuss three cases in which endodontic pathology was initially recognized but subsequent follow-up revealed severe osteolytic fungal infection of the maxilla manifesting as acute apical abscesses in the maxillary canine region. CBCT demonstrated osteolytic abnormalities, and further histology confirmed the illness was caused by mucormycosis in patients with uncontrolled diabetes mellitus and exposure to COVID-19.
Insights
Fungal osteomyelitis, a severe infection, can manifest as dental abscesses. This study highlights three cases of maxillary mucormycosis in diabetic patients, emphasizing the need for prompt diagnosis and treatment.
Area of Science:
- Dentistry
- Infectious Diseases
- Mycology
Background:
- Fungal osteomyelitis is a rare but serious opportunistic infection.
- It can present insidiously, complicating initial dental diagnoses.
- Early recognition is crucial for effective management.
Observation:
- Three cases of maxillary osteomyelitis initially presenting as endodontic pathology are discussed.
- Patients developed severe osteolytic lesions in the maxilla, mimicking acute apical abscesses.
- Cone-beam computed tomography (CBCT) revealed significant osteolytic abnormalities.
Findings:
- Histopathology confirmed mucormycosis as the causative fungal agent in all three cases.
- Patients had uncontrolled diabetes mellitus and a history of COVID-19 exposure.
- The infection manifested in the maxillary canine region.
Implications:
- This highlights a potential severe complication in immunocompromised patients, particularly those with diabetes.
- Endodontists and clinicians should consider fungal infections in refractory or severe cases.
- Prompt diagnosis and multidisciplinary management are essential for improving outcomes in fungal osteomyelitis.
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