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Updated: Sep 4, 2025
Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
Conditional relative survival among patients with chronic lymphocytic leukaemia: A population-based study in the
Lina van der Straten1,2,3, Mark-David Levin2, Otto Visser4
1Department of Research and Development Netherlands Comprehensive Cancer Organisation (IKNL) Utrecht The Netherlands.
Abstract:
Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up-to-date estimates of 5-year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post-diagnosis among CLL patients diagnosed during 2007-2020. We showed that 5-year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel-based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared to an age- and sex-matched group from the general population.
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