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Deep venous sinus thrombosis with right thalamic infarction in a young patient after COVID-19 vaccination

Suraj Sharma1, Prakash Dhakal1, Abhishek Sharma1

  • 1Department of Radio-Diagnosis and Imaging, National Academy of Medical Sciences, Kathmandu, Nepal.

Radiology Case Reports
|July 18, 2022
PubMed

Insights

Cerebral venous sinus thrombosis is rare but treatable. This case highlights deep cerebral venous sinus thrombosis in an adolescent post-COVID-19 vaccination, presenting with thalamic infarction.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Radiology

Background:

  • Cerebral venous thrombosis (CVT) is a rare cerebrovascular disease, accounting for 0.5% of cases.
  • While treatable if diagnosed early, CVT has various risk factors.
  • Recent reports suggest a potential link between COVID-19 vaccination and cerebral venous sinus thrombosis.

Observation:

  • An adolescent female presented with imaging evidence of deep cerebral venous sinus thrombosis and right thalamic infarction.
  • The patient had recently received a COVID-19 vaccine.
  • Laboratory results indicated microcytic hypochromic anemia.

Findings:

  • Imaging, including CT head, MRI, and MRV, confirmed thrombosis of the deep venous (galenic) system.
  • Vasogenic edema was observed in the bilateral thalami and left caudate nucleus.
  • Areas of infarction were identified in the right thalamus.

Implications:

  • This case underscores the importance of considering CVT in young individuals post-COVID-19 vaccination, especially with neurological symptoms.
  • Early diagnosis and prompt treatment with anticoagulation are crucial for favorable outcomes.
  • Further research is warranted to elucidate the potential association between COVID-19 vaccines and CVT.

Keywords:
Cerebral venous sinus thrombosis (CVST)Cerebral venous thrombosis (CVT)Thalamic infarct

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