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Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes
Published on: November 23, 2021
Research Progress on Multifunctional Fluorescent Probes for Biological Imaging, Food and Environmental Detection
1Beijing Key laboratory of Flavor Chemistry, Beijing Technology and Business University, Beijing, PR China.
Abstract:
There has been rapid progress in the development of fast, sensitive, cheap and low-cytotoxicity micro-molecule fluorescent probes for application in various fields, including disease diagnosis, food safety and environmental safety. As an analytical tool, dual-function fluorescent probes with dual-emission responses have attracted considerable attention due to their cost-effectiveness and efficiency over single-function sensors. This review primarily describes research progress on multifunctional probes in terms of the reaction type and coordination type, as well as the general design principles of probes. The analytes include reactive oxygen species (ROS), reactive sulfur species (RSS), harmful cations and anions, etc. Multifunctional probes for food, medical and environmental applications are listed for future research. To improve the development of rapid detection methods, trends and strategies in the development of multifunctional fluorescent probes are also discussed.
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