Related Experiment Video
Updated: Sep 4, 2025

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Pearls & Oy-sters: Cerebral Venous Congestion Associated With Cognitive Decline Treated by Jugular Release
Christopher T Primiani1, Michael Lawton2, Argye Elizabeth Hillis2
1From the Department of Neurology (C.T.P., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD; Department of Neurosurgery (M.L.), Barrow Neurological Institute, Phoenix, AZ; and The Russell H. Morgan Department of Radiology and Radiological Sciences (F.K.H.), Johns Hopkins Hospital, Baltimore, MD. cprimiani@jhmi.edu.
Abstract:
Cognitive dysfunction is often multifaceted and can be seen across all age groups in medicine. The combination of cognitive decline and increased intracranial pressure may suggest possible anatomical abnormalities. We present a case report from our academic center that describes a young man with new cognitive fatigue and brain fog in the setting of increased venous pressure that resolved with surgical intervention at a site of jugular vein stenosis. We discuss current hypotheses from basic and clinical research related to pathophysiology underlying venous vascular congestion and associated neurologic disorders. Further research is warranted to elucidate the underlying mechanisms of venous congestion and cognition to better identify therapies and improve quality of life for patients.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Venous Thrombosis IV: Nursing Management
Aneurysm IV: Nursing Management
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Vascular Spasm

