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Updated: Sep 4, 2025

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
Published on: November 30, 2016
[Development of Multimodal Intervention in Cancer Cachexia]
1Division of Thoracic Oncology, Shizuoka Cancer Center.
Abstract:
Cancer cachexia is a combination of metabolic abnormalities associated with malignancy and symptoms that interfere with eating behavior and physical activity, resulting in weight loss. A multimodal treatment proven to be safe and effective has yet to be established. However, with the approval of anamorelin hydrochloride, clinical studies are underway to combine pharmacological and non-pharmacological treatment. It is important to build a multidisciplinary team that includes nutritionists, physiotherapists, physicians, nurses, and psychotherapists, each with a clearly defined role. This also requires education on cancer cachexia not only for healthcare professionals but also for patients and their families.
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