Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Microcirculatory consequences of hemorheologic disorders].

M R Boisseau, G Freyburger, M F Lorient-Roudaut

    Journal Des Maladies Vasculaires
    |January 1, 1987
    PubMed
    Summary

    Hemorheologic blood diseases, like sickle cell anemia, directly impact red blood cell microcirculation and thrombosis. Acquired vascular disorders indirectly link hemorheology to blood flow issues, with potential pre-thrombotic states.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The Thrombodynamics® analyzer: A new thrombin generation analyzer compared to the Calibrated Automated Thrombogram® in liver transplantation.

    Thrombosis research·2019
    Same author

    Multiplate<sup>®</sup> evaluation of acetylsalicylic acid efficacy in carotid surgery: routine and genetic influencing factors.

    Journal of thrombosis and haemostasis : JTH·2018
    Same author

    Re: 'Prothrombin G20210 Mutation and Lower Extremity Peripheral Arterial Disease: A Systematic Review and Meta-analysis'.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2015
    Same author

    Rotation thromboelastometry detects thrombocytopenia and hypofibrinogenaemia during orthotopic liver transplantation.

    British journal of anaesthesia·2010
    Same author

    Chronic venous disease.

    Minerva cardioangiologica·2007
    Same author

    Bcr-abl translocation can occur during the induction of multidrug resistance and confers apoptosis resistance on myeloid leukemic cell lines.

    Cell death and differentiation·2006

    Area of Science:

    • Hematology
    • Vascular Biology
    • Pathophysiology

    Context:

    • Microcirculation is significantly affected by hemorheologic blood diseases, particularly disorders of red blood cells.
    • Sickle cell anemia serves as a prime example of a hemorheologic disease, elucidating the intricate relationship between hemorheology, microcirculation, and thrombosis.

    Purpose:

    • To explore the direct and indirect relationships between hemorheologic blood disorders and microcirculation.
    • To investigate the role of hemorheologic disorders in vascular occlusion and their impact on blood flow.
    • To highlight the pharmacological potential in managing these conditions.

    Summary:

    • Direct links exist between hemorheologic diseases (e.g., sickle cell anemia) and red blood cell microcirculation, affecting thrombosis.
    • In acquired vascular disorders, hemorheologic issues indirectly predispose to vascular lumen occlusion and pre-thrombotic states, impacting microcirculation.
    • The precise role of endothelial cells and the vascular wall in these occlusive phenomena remains undetermined.

    Impact:

    • Understanding these relationships is crucial for developing targeted therapies for hemorheologic and vascular diseases.
    • Pharmacological interventions targeting cellular, intercellular, and parietal activities hold significant therapeutic promise.
    • Further research into the vascular wall's role could unveil new therapeutic strategies.

    Related Experiment Videos