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Updated: Sep 4, 2025

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
Published on: November 3, 2015
Pulsatile flow of thixotropic blood in artery under external body acceleration
Louiza Cheffar1, Abdelhakim Benslimane1, Djamel Sadaoui1
1Laboratoire de Mécanique, Matériaux et Energétique (L2ME), Faculté de Technologie, Université de Bejaia, Bejaia 06000, Algérie.
Abstract:
This work presents a numerical technique for simulating non-Newtonian blood flow in human's arteries driven by an oscillating pressure gradient. The blood is considered as a thixotropic fluid and its structural properties are considered to obey Moore's thixotropic model as a constitutive equation. The equations of motion are simplified considering the flow laminar, axisymmetric and the fluid incompressible. A numerical solution is presented using finite difference method in order to compute the velocity field and wall shear stress distribution. The numerical results obtained have been validated with the analytical solution available in the literature. Furthermore, the effect of the structural properties, the average of the pressure gradient and the external acceleration on the velocity and wall shear stress distribution is investigated. These results reveal the influence of the different parameters studied on the pipe flow response of the thixotropic fluid.
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