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Tramadol Versus Codeine in Hand Surgery.

Jacob Tulipan1, Jack Abboudi1, Mark L Wang1

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PubMed
Summary
This summary is machine-generated.

Tramadol and codeine prescriptions for upper extremity pain show different refill patterns. Patients on tramadol, especially older individuals and those treated nonoperatively, required more refills than those on codeine.

Keywords:
codeinehand surgeryopioidpain managementtramadol

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Area of Science:

  • Orthopedics
  • Pain Management
  • Pharmacology

Background:

  • Tramadol and codeine are frequently prescribed for upper extremity pain following surgery or injury.
  • While similar in opioid receptor affinity, their pharmacological profiles differ, suggesting non-interchangeability.

Purpose of the Study:

  • To compare the prescribing and refill patterns of tramadol and codeine in hand surgery patients.
  • To test the hypothesis that prescribing and refill patterns for these analgesics are similar.

Main Methods:

  • Analysis of all tramadol and codeine prescriptions issued by hand surgeons over a one-year period.
  • Comparison of prescription amounts (in morphine equivalents) and refill frequencies between the two drugs.

Main Results:

  • Patients receiving tramadol required significantly more refills than those on codeine, despite similar morphine equivalent dosages.
  • Older patients and those treated nonoperatively were more likely to receive tramadol and require refills.
  • Nonoperative patients received significantly more tramadol than surgically treated patients.

Conclusions:

  • Tramadol and codeine are not equivalent for managing upper extremity pain.
  • Further research is needed to guide optimal selection between tramadol and codeine based on patient and clinical factors.