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Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function
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Obstetric tetanus in an immunized patient.
Junior Principe-Collazos1, Anthony Ramos-Yataco2, Antony Gonzalo Gonzáles Uribe3
1Universidad Nacional Mayor de San Marcos, Escuela de Medicina de San Fernando, Av. Miguel Grau 755, Cercado de Lima 15001, Peru.
Idcases
|July 20, 2022
Summary
Obstetric tetanus, a rare infection from Clostridium tetani, occurred in a Peruvian woman post-delivery despite immunization. This case highlights the need for vigilance in postpartum care, even in areas with no prior reports.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Microbiology
Background:
- Obstetric tetanus is a severe infection caused by Clostridium tetani.
- It occurs during pregnancy or within six weeks of delivery.
- No prior cases of obstetric tetanus have been reported in Peru.
Observation:
- A puerperal woman in Peru presented with obstetric tetanus.
- The patient had undergone curettage for postpartum hemorrhage.
- She was reportedly immunized against tetanus.
Findings:
- This represents the sixth reported case of obstetric tetanus globally.
- The case occurred despite documented tetanus immunization.
- It underscores potential gaps in vaccine efficacy or exposure risks.
Implications:
- Highlights the importance of continued tetanus surveillance in postpartum women.
- Suggests a need to re-evaluate tetanus prevention strategies in endemic or previously unaffected regions.
- Emphasizes that postpartum hemorrhage interventions may present unique risks for tetanus exposure.
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