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Published on: February 5, 2019
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[Colostrum protocol evaluation for very low birth weight preterm infants].
Marcia Maraboli Aguilera1, Graciela Lavanderos Bustamante1, Camila León Martínez1
1Complejo Aslsteoclal Dr. Sótero del Río, Santiago, Chile.
Andes Pediatrica : Revista Chilena De Pediatria
|July 20, 2022
Summary
Early colostrum for very-low-birth-weight (VLBW) preterm infants improved breastfeeding rates and milk volume at discharge. This practice offers significant benefits for VLBW infant care.
Area of Science:
- Neonatal Medicine
- Pediatrics
- Clinical Nutrition
Background:
- Oral colostrum administration is a recommended practice for very-low-birth-weight (VLBW) preterm infants.
- The clinical impact of early colostrum on infant outcomes and maternal lactation requires further evaluation.
Purpose of the Study:
- To assess the clinical effects of early oral colostrum administration on in-hospital outcomes.
- To evaluate the impact on lactation in VLBW preterm infants compared to historical controls.
Main Methods:
- A descriptive cohort study with historical controls was conducted.
- Infants under 1500 grams were included, with exclusions for specific maternal and infant conditions.
- Perinatal, morbidity, nutritional, and breastfeeding data were compared between groups.
Main Results:
- No significant differences were found in infectious, respiratory, or gastrointestinal morbidity, enteral feeding progression, parenteral nutrition duration, or hospital stay.
- A significant increase in breastfeeding at discharge (52% vs. 69%) and breast milk volume (70 vs. 102 ml/kg/day) was observed in the post-colostrum group.
- Groups were comparable in perinatal history.
Conclusions:
- Early colostrum administration in VLBW preterm infants is associated with increased maternal milk volume at discharge.
- This practice demonstrates a positive benefit for VLBW preterm infant care, particularly concerning lactation support.

