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Cancer clinical trials in the Philippines
Michelle Ann B Eala1, Patricia Anne S Basilio2, Edward Christopher Dee3
1College of Medicine, University of the Philippines, 547 Pedro Gil Street, 1000, Manila, Philippines. mbeala1@up.edu.ph.
Cancer Causes & Control : CCC
|July 20, 2022
Summary
Cancer research in the Philippines faces significant resource and access disparities, particularly for clinical trials. Addressing geographic, registry, and sociocultural barriers is crucial for equitable cancer care in lower-middle-income countries.
Area of Science:
- Oncology
- Clinical Trials
- Health Disparities
Background:
- Cancer is the fourth leading cause of death in the Philippines, a lower-middle-income country.
- Clinical trials and research institutions are concentrated in Luzon, creating geographic access issues.
- Limited cancer patient and clinical trial registries hinder awareness and participation.
Purpose of the Study:
- To discuss disparities in cancer trial resources and access in the Philippines.
- To highlight sociocultural and economic factors influencing clinical trial participation.
- To propose actionable solutions for improving cancer research equity.
Main Methods:
- Commentary based on the perspective of the Philippines.
- Analysis of geographic, registry, and sociocultural barriers.
- Identification of financial toxicities in cancer care.
Main Results:
- Geographic centralization of trials in Luzon.
- Lack of comprehensive national registries.
- Sociocultural factors like family involvement, health literacy, and economic burden impact participation.
Conclusions:
- Bolster locally led trials and international collaboration to enhance diversity and generalizability.
- Strengthen national registries to improve patient eligibility awareness.
- Integrate cultural competency frameworks promoting trust and collaboration in research.
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