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Ischemia-Modified Albumin (IMA) levels in ectopic pregnancy and early pregnancy loss
K Dogan1, C Helvacioglu1, S Baghaki1
1Department of Obstetrics and Gynecology, University of Health Sciences Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital, Istanbul, Turkey.
Background:
IMA is a novel marker to consider in ischemic conditions. The initial stages of pregnancy represent a physiological ischemic status. IMA levels may be changed when there is suspicion of early pregnancy complications because of increased oxidative stress.
Aim:
We aimed to determine and compare IMA values in cases of ectopic and healthy pregnancies as well as early pregnancy loss.
Methods:
This prospective case control study population (n = 91) consisted of early pregnancy loss (n = 28), ectopic pregnancy (n = 28), and an intracavitary early healthy pregnancy (n = 35). The serum IMA levels were compared in these groups.
Results:
Demographic parameters were similar and there was no significant difference between the three groups in terms of serum IMA concentrations.
Conclusion:
We suggested that IMA cannot be used clinically for the diagnosis and follow up of early pregnancy complications during the first five to six gestational weeks.
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