Related Experiment Video
Updated: Sep 4, 2025
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Castration-resistant prostate cancer with metastasis to external auditory canal - Case report
Naoki Akagi1, Koichi Oshima1, Koji Fukui1
1Department of Urology, Takarazuka City Hospital, Japan.
Abstract:
We report a case of castration-resistant prostate cancer metastasis to an external auditory canal. A 68-year-old man was diagnosed with prostate cancer (cT3aN1M1b GS5+5). Although abiraterone, docetaxel, and cabazitaxel were administered, and PSA decreased, liver metastasis appeared. Hearing loss in the left ear was also noted and the patient was referred to an otolaryngologist for an examination, which showed a neoplastic lesion in the external auditory canal. Biopsy findings resulted in a diagnosis of adenocarcinoma. Presented here are details of a rare case of prostate cancer with metastasis to an external auditory canal.
Insights
This rare case highlights prostate cancer spreading to the external auditory canal, even after treatment. It underscores the importance of considering unusual metastasis sites in advanced prostate cancer.
Area of Science:
- Oncology
- Otolaryngology
Background:
- Prostate cancer is a common malignancy in older men.
- Castration-resistant prostate cancer (CRPC) presents therapeutic challenges.
- Metastasis can occur to various distant sites.
Observation:
- A 68-year-old man with CRPC developed left-sided hearing loss.
- Examination revealed a neoplastic lesion in the external auditory canal.
- Biopsy confirmed adenocarcinoma metastasis.
Findings:
- This is a rare instance of CRPC metastasizing to the external auditory canal.
- The patient had previously received abiraterone, docetaxel, and cabazitaxel.
- Liver metastasis was also present despite treatment.
Implications:
- This case expands the known spectrum of CRPC metastasis.
- It emphasizes the need for thorough otological evaluation in CRPC patients with ear symptoms.
- Understanding rare metastatic patterns aids in comprehensive patient management.
