Impact of diabetes on long-term all-cause re-hospitalization after revascularization with percutaneous coronary
Kirstine N Hansen1, Manijeh Noori1, Evald H Christiansen2
1Department of Cardiology, 11286Odense University Hospital, Odense, Denmark.
Insights
Over half of diabetes patients undergoing percutaneous coronary intervention (PCI) face readmission within a year. Comorbidities strongly predict non-ischemic heart disease readmissions, but not IHD-related ones.
Area of Science:
- Cardiology
- Diabetology
- Public Health
Background:
- Diabetes mellitus is a significant risk factor for cardiovascular diseases.
- Percutaneous coronary intervention (PCI) is a common revascularization procedure for coronary artery disease.
Purpose of the Study:
- To investigate the incidence, causes, and probability of re-hospitalization within 30 and 365 days after PCI in patients with diabetes.
- To identify predictors of readmission in this patient population.
Main Methods:
- A retrospective study of 2763 patients with diabetes treated with PCI between January 2010 and September 2014.
- Analysis of reasons for readmission within 30 and 365 days, including ischemic heart disease (IHD) and non-IHD causes.
- Statistical analysis to identify predictors of readmission, including gender, type of myocardial infarction, age, and Charlson Comorbidity Index (CCI).
Main Results:
- Readmission rates were 18% within 30 days and 58% within 365 days.
- Ischemic heart disease (IHD) was the reason for readmission in 27% of cases, while non-IHD reasons accounted for 31%.
- Female gender and non-ST-segment elevation myocardial infarction were associated with IHD-related readmissions. Age and higher CCI scores (≥3) predicted non-IHD-related readmissions.
Conclusions:
- More than half of patients with diabetes undergoing PCI are readmitted within one year.
- Comorbidities are a strong predictor for non-IHD-related readmissions but do not increase the risk for IHD-related readmissions.
- Understanding these predictors can inform strategies to reduce readmission rates in diabetic patients post-PCI.
Purpose:
The purpose of the study was to investigate the incidence, cause and probability of re-hospitalization within 30 and 365 days after percutaneous coronary intervention (PCI) in patients with diabetes.
Method:
Between January 2010 and September 2014, 2763 patients with diabetes were treated with PCI at two Hospitals in Western Denmark. Reasons for readmission within 30 and 365 days were identified.
Results:
Readmission risks for patients with diabetes were 58% within 365 days and 18% within 30 days. Reason for readmission was ischemic heart disease (IHD) in 725 patients (27%), and non-IHD-related reasons in 826 patients (31%). IHD-related readmission within 365 days was associated with female gender (OR 1.3, 95% CI: 1.1-1.5), and non-ST-segment elevation myocardial infarction, compared to stable angina at the index hospitalization (OR 1.3, 95% CI: 1.1-1.6). Among patients with diabetes, increased risk of readmission due to other reasons were age (OR 1.3, 95% CI: 1.2-1.5) and higher scores of modified Charlson Comorbidity index (CCI): CCI ≥3 (OR 3.6, 95% CI: 2.8-4.6).
Conclusion:
More than half of the patients with diabetes mellitus undergoing PCI were readmitted within 1 year. Comorbidities were the strongest predictor for non-IHD-related readmission, but did not increase the risk for IHD-related readmissions.
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